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To account for their observations, they suggested a ‘sliding-filament’ model in which myosin filaments run the length of the A-band and actin filaments slide into this band when muscle shortens.
Terrell L. Hill, George M. White, On the Sliding-Filament Model of Muscular Contraction, III. Kinetics of Cross-Bridge Fluctuations in Configuration, Proceedings of the National Academy of Sciences of ...
It is the 50th anniversary of the internationally-renowned "sliding filament" theory, developed by Professor Jean Hanson and her colleague Professor Hugh Huxley. The ground-breaking discovery ...
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