Doctors sometimes treat neuroblastoma with 13-cis-retinoic acid (also called Isotretinoin, or 13-cis-RA). But we know from earlier studies that when everyone has the same dose, some people will have a ...

Retinoic acid regulates transcription by interacting with nuclear retinoic acid receptors, which bind to retinoic acid response elements near target genes. Recent studies have refined our ...

Retinoic Acid Receptor (RARs) Agonist: Pipeline Development Activities. The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage.

Retinoic acid (RA), the active form of vitamin A, is a small lipophilic molecule that acts as a signalling molecule in vertebrates by binding to nuclear receptors (heterodimers of RA receptors and ...

Retinoic acid is a light-sensitive compound, like other retinoids, because of the alternating double bonds between the carbon atoms in its hydrophobic tail, which is attached to a 6-carbon ring.

To date scientists have known that retinoic acid in the gut-draining lymph nodes promotes effector CD8 T cell migration to the intestines, enhancing the immune response.

Retinoic acid gradient visualized for the first time in an embryo Date: April 7, 2013 Source: RIKEN Summary: In a ground-breaking study, researchers report a new technique that allows them to ...

Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-025-57185-y Cite This Page : ...

All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%. Pilot studies of treatment with arsenic triox ...