This was a study to learn more about the drug 13-cis-retinoic acid which doctors use to treat children and young people with high risk neuroblastoma. Doctors sometimes treat neuroblastoma with ...

Retinoic acid (RA) was first implicated as a signalling molecule on the basis of its teratogenic effects on limb patterning. Studies in chick using treatment with RA or RA receptor antagonists ...

Retinoic acid (RA) has complex and pleiotropic functions during vertebrate development. Recent work in several species has increased our understanding of the roles of RA as a signalling molecule ...

Retinoic acid is a light-sensitive compound, like other retinoids, because of the alternating double bonds between the carbon atoms in its hydrophobic tail, which is attached to a 6-carbon ring.

Retinoic acid upregulates genes that promote survival in adverse conditions. It induces differentiation, inhibits proliferation, induces apoptosis and has strong antioxidant activity.

All- trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%. Pilot studies of treatment with arsenic ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

Why Retinol?“Retinol is going to be a great option for somebody who's looking to target fine lines, wrinkles, skin texture, ...

Retinoic Acid Receptor (RARs) Agonist: Pipeline Development Activities The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage.

To date scientists have known that retinoic acid in the gut-draining lymph nodes promotes effector CD8 T cell migration to the intestines, enhancing the immune response.

Retinoic acid is important in the development of human embryos too, telling the cells where to grow a head, heads and feet, Monaghan explained.

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. St. Jude Children’s Research Hospital scientists resolved the ...