Researchers report that myelin breakdown results in an accumulation of very long-chain fatty acids (VLCFA) and their intermediates, which triggers an autoimmune response that damages brain cells.

Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, is a notable hallmark of multiple sclerosis (MS) and related neurodegenerative disorders such as ...

The first signs of multiple sclerosis (MS) may appear much earlier than most doctors once believed. A new study suggests that ...

Secondary progressive multiple sclerosis (SPMS) can be active or inactive. Learn about the differences and how it impacts treatment.

"In terms of association with climate, our results suggest a relationship between enhancing lesions and tropical nights, a variable indicating extreme temperatures, which had not been previously ...

Vision loss, balance problems, numbness, and sensitivity to heat could be early signs and symptoms of multiple sclerosis.

Multiple sclerosis (MS) is a chronic inflammatory disorder that is thought to impact about 2.3 million people around the world. This disorder is characterized by the loss of a protective neuronal ...

—Using CDC data, researchers in Pakistan have found that annual age-adjusted mortality rates due to multiple sclerosis in the U.S. rose between 1999 and 2020, a trend that was observed across both ...

Some research suggests that people with multiple sclerosis are at a higher risk of atherosclerosis. An increased risk hasn’t been established, and we don’t know how MS might increase the risk. Having ...

Multiple sclerosis (MS) is characterized by a broad array of symptoms. Despite this variability, most individuals with MS will exhibit a distinct set of symptoms during their initial clinical attack.

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterised by the progressive loss of motor neurons, leading to muscle weakness, paralysis and, ultimately, ...