the mouse has become the model of choice. Here the authors re-examine the value of this mouse model as a tool for understanding human diabetes and for testing potential therapies, reviewing both ...

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's ...

Selecting an appropriate mouse model is one of the most important decisions a pre-clinical researcher can make. Which is best suited for immuno-oncology? Cancer research and drug discovery has ...

Every year, over 1.5 million new cases of prostate cancer are diagnosed throughout the world. As one of the leading causes of ...

A well-characterized in vivo model of a1AT mutant Z liver injury, the PiZ mouse, is useful to better understand the pathways involved in this disease. The results of the referenced study show an ...

They created a mouse model that recapitulates the early non-motor symptoms as well as the motor difficulties in Parkinson's disease in a manner that directly mimics the condition in many patients.

Scientists from the Cardiovascular Research Center at the University of Virginia School of Medicine and Astrazeneca plc have developed a new mouse model of cardiovascular disease associated with ...