New molecular mechanism of neuropathic pain in mice Date: July 14, 2015 Source: Hiroshima University Summary: A research group has demonstrated that the downregulation of spinal astrocyte ...

The current neuropathic pain study by Li and Tolias used mouse models of neuropathic pain caused by nerve injury, chemotherapy or diabetes.

New molecular mechanism of neuropathic pain in mice Peer-Reviewed Publication Hiroshima University image: This image shows a summary of this study. view more Credit: Hiroshima University ...

A research group from Hiroshima University demonstrated that the downregulation of spinal astrocyte connexin43 (Cx43) expression causes sustained neuropathic pain following peripheral nerve injury.

Spinal cord astrocytes are critical in the maintenance of neuropathic pain. Cx43 expressed on spinal dorsal horn astrocytes modulates synaptic neurotransmission, but its role in nociceptive ...

A research group from Hiroshima University demonstrated that the downregulation of spinal astrocyte connexin43 (Cx43) expression causes sustained neuropathic pain following peripheral nerve injury.

The mouse spares nerve injury model is helping researcher understand neuropathic pain.

In a paper published in the journal Neuron, researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic ...

Certain personality traits such as sociability, anxiety or depression influence manifestations of neuropathic pain in mice, according to a new study by the Neuropharmacology Laboratory-NeuroPhar ...

Now in a study published in the journal Antioxidants, they have analyzed the effects of administering to mice models of neuropathic pain water enriched with hydrogen molecules, a treatment that ...