We and others have shown that σ2R/TMEM97 ligands alleviate mechanical hypersensitivity in mouse neuropathic pain models with a time course wherein maximal antinociceptive effect is approximately ...

Boston Children's Hospital and Harvard Medical School researchers have discovered a neuroimmune communication pathway that ...

No less than 16 different types of nerve cells have been identified by scientists in a new study on the human sense of touch.

Dietmar Thal, Prof. Bart De Strooper, and Dr. Sriram Balusu demonstrates they can indeed prevent loss of nerve cells in a mouse model of Alzheimer's using specific inhibitors. "Nerve cells die in ...

A team of researchers at KU Leuven and VIB explored the molecular sequence of events in this cellular demise and identified specific inhibitors that could prevent the loss of nerve cells in different ...

More information: Mikael Åkerlund et al, Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort, Pain (2024). DOI: 10.1097/j.pain.0000000000003463 ...

The study used the paclitaxel (PTX) model, in which a common chemotherapy drug, PTX, was administered to mice to induce neuropathic pain. Also Read: MIRA Pharmaceuticals’ Oral Ketamine Analog ...

Dietmar Thal, Prof. Bart De Strooper, and Dr. Sriram Balusu demonstrates they can indeed prevent loss of nerve cells in a mouse model of Alzheimer's using specific inhibitors. "Nerve cells die in ...