Malic enzymes are widely distributed in nature and have many biological functions. The crystal structure of human mitochondrial NAD (P)+-dependent malic enzyme in a quaternary complex with NAD+ ...

Mechanism identified behind enzyme involved in liver and other human cancers Date: December 7, 2017 Source: Uppsala University Summary: To understand what has gone wrong when cancer occurs and to ...

CLEVELAND - Researchers at the Case Western Reserve University School of Medicine have identified a cellular mechanism that is critical in maintaining normal cell function. In their work, the ...

International team led by University of Leicester unveil a hidden step in enzyme mechanism.

Co-investigator Nakamura studies obesity and molecular metabolism mechanisms and will use his expertise to study how the enzyme regulates liver metabolism through lysosome function in animal models.

DEAD-box proteins, which are ancient enzymes found in all forms of life, function as recycling "nanopistons." They use chemical energy to clamp down and pry open RNA strands, thereby enabling the ...

Enzymes help with specific functions that are vital to the operation and overall health of the body. They help speed up chemical reactions in the human body. They are essential for respiration ...

The Nocturnin enzyme modifies two critical metabolic molecules, NADP+ and NADPH, by removing a phosphate group from each to produce NAD+ and NADH, respectively. NAD+ and NADH are essential to the ...

Scientists studying a COVID-19 coronavirus enzyme at temperatures ranging from frosty to human-body warm discovered subtle structural shifts that offer clues about how the enzyme works. The ...

A new study suggests an enzyme unique to Homo sapiens may have made us more competitive water seekers than our closest ...

A Key Enzyme A new study has been able to extend the lifespan of worms and flies by inhibiting RNA polymerase III (Pol III). Since the enzyme is common to all animal species, including humans ...