You can subtract multiple cells from one cell in Excel by using Minus sign, SUM function and Paste Special feature. Here is a tutorial on this.

Create a formula to add or subtract data in Excel by using cell numbers Above, we have seen a simple method to create a formula to add or subtract data in Excel.

Like we already mentioned, there’s no actual command in Excel for subtracting values, you have to use an operator in a formula. That said, we can create individual formulas in cells.