Glutamate excitotoxicity mediated by the AMPA/kainate type of glutamate receptors damages not only neurons but also the myelin-producing cell of the central nervous system, the oligodendrocyte1.

Excitotoxicity is the pathological process by which neurons are damaged and killed by the overactivations of receptors for the excitatory neurotransmitter glutamate, such as the NMDA receptor and ...

These prevented excitotoxicity (right). [Courtesy of Yan et al., 2020 Science/AAAS.] Yan found that TwinF bound to a stretch of 18 amino acids on the cytosolic side of GluN2A and GluN2B, close to the ...

This is known as excitotoxicity. Researchers have been studying therapies that attempt to inhibit glutamate activity for the treatment of ALS , as noted by the ALS Association .

NMDA Receptor & Glutamate Excitotoxicity . Glutamate is a predominant excitatory neurotransmitter in the mammalian CNS. When intensely activated, ...

In recent years, glutamate ‘excitotoxicity’ has been proposed as a mechanism by which retinal ganglion cells die in glaucoma. 1 If true, this could lead to exciting new treatments for glaucoma.

Glutamate is the most important of the excitatory neurotransmitters and its mechanism is fundamental for memory processes. ..

Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for depression, bipolar disorder, and more.

2. Asian Sauces. Soy sauce, fish sauce, and oyster sauce all have very high levels of glutamate. Soy is naturally high in glutamate, and soy-based sauces will have concentrated levels of the compound.