The 2 x 2 factorial design has been advocated for improving the efficiency of clinical trials. Most such trials are designed on the assumption that there is no interaction between the levels of the ...

Fractional factorial designs are widely used in various scientific investigations and industrial applications. Level permutation of factors could alter their geometrical structures and statistical ...

In the present investigation, the fixed-dose combination (FDC) tablet of Atorvastatin calcium and Ezetimibe was prepared by a quality-by-design approach using two-level factorial design. In the ...