The problem of minimizing a concave function subject to linear inequality constraints may have many local solutions. Therefore, finding the global constrained minimum is a computationally difficult ...

ε ~ N(0, 0.5 2) to the response. Holsclaw, T., Sanso, B., Lee, H. K., Heitmann, K., Habib, S., Higdon, D., & Alam, U. (2013). Gaussian process modeling of derivative ...

However, such functional leaps by combination of unrelated domains have not been directly demonstrated. Here we show that highly specific and complex protein functions can be generated by joining a ...

However, several studies involving p53 core domain mutants suggested that regulatory functions in recombinative repair do not require transcriptional transactivation and are separable from growth ...