When you connect your Excel, Tableau or QlikView to your Hadoop data in Cloudera, Hortonworks, or MapR, you are connecting via a Simba ODBC Driver. Simba, a twenty-year veteran in the industry, ...

Use the Excel file as an ODBC data source (connection string info here), and your MySQL database as the destination (using their ODBC connector). What OS is your process running on?