In a major leap forward for genetic and biomedical research, scientists have developed a powerful new artificial intelligence tool that can predict the 3D shape of chromosomes inside individual ...

Applying these methods to human cell lines, we found that synergies were enriched in enhancers and promoters in active chromatin and in highly transcribed and lineage-defining genes. In prostate ...

New AI tool reveals single-cell structure of chromosomes — in 3D A breakthrough at the University of Missouri could help scientists better understand how genes work — and how certain types of ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types.

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo ...