The case-control study design is often used in the study of rare diseases or as a preliminary study where little is known about the association between the risk factor and disease of interest.

A case-control study, like other medical research, can help scientists find new medications and treatments. Find out how 'cases' are compared with 'controls' in this type of study. This type of ...

Bryan Langholz, David Clayton, Sampling Strategies in Nested Case-Control Studies, Environmental Health Perspectives, Vol. 102, Supplement 8: Biostatistics in the Study of Human Cancer (Nov., 1994), ...

There are a number of possible designs for case-control studies. The simplest uses two separate simple random samples, but an actual study may use more complex sampling procedures. Typically, ...

In a nationally representative sample of 1.1 million homes, we compared the prevalence of smoking among 33,000 deceased women and 41,000 deceased men (case subjects) with the prevalence of smoking ...

The aim of INTERHEART, a case-control study conducted in > 50 countries, was to determine the associations between a wide array of risk factors and AMI within populations defined by ethnicity and ...

We conducted a multicenter, nested case–control study of Alzheimer’s disease biomarkers in cognitively normal participants who were enrolled in the China Cognition and Aging Study from January ...

Report of a matched case-control study to evaluate cancer risk factors, including molecular testing in Southern Brazil ...