癌症干细胞：肿瘤治疗的终极标靶 癌症干细胞（CSCs）是肿瘤中具有自我更新、多向分化和致瘤能力的特殊亚群，其独特的生物学特性使其成为治疗抵抗和复发的根源。研究表明，仅需100个CD133 + 的胶质母细胞瘤干细胞即可在小鼠中诱发肿瘤，而10万个CD133 - 的普通肿瘤细胞则无此能力。这种强大的 ...

CSCs are capable of undergoing unlimited cell division while retaining their stem cell identity (self-renewal) and giving rise to more differentiated cells with limited or no tumour-initiating and ...

综述：癌症干细胞 (CSCs)的生物学特性、治疗抵抗机制及靶向治疗新策略 《Signal Transduction and Targeted Therapy》：Cancer stem cells: landscape, challenges and emerging therapeutic innovations 【字体： 大 中 小 】 时间：2025年08月06日 来源：Signal ...

Thirdly, niche and systemic regulatory mechanisms of CSCs were summarized, including niche cells such as tumor non-stem cells, immune cells, endothelial cells, fibroblasts, neurons and fat cells ...