The new system developed by Professor Chad Mirkin delivers CRISPR machinery more safely and effectively into cells.

Researchers have unveiled a new type of nanostructure that dramatically improves CRISPR delivery. Called lipid nanoparticle ...

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, ...

Orders for new CRISPR enzymes can be placed at www.idtdna.com/AldevronCRISPRnucleases. “IDT and Aldevron are united in accelerating CRISPR research worldwide by ...

本研究针对传统CRISPR-Cas系统挖掘方法的局限性，创新性地采用进化尺度语言模型（ESM）开发了AIL-Scan策略，成功鉴定了7种未记录的Cas12a亚型。通过整合机器学习与结构生物学技术，揭示了这些亚型独特的PAM识别特性和核酸酶活性，首次实现了无需传统PAM序列的 ...

本研究通过全基因组CRISPR/Cas9筛选发现组蛋白甲基转移酶SUV39H2是口腔鳞癌(OSCC)抵抗溶瘤病毒oHSV-1的关键因子。研究人员证实 ...

CRISPR has revolutionized science. AI is now taking the gene editor to the next level. Despite its real-world impact, CRISPR isn’t perfect. The tool snips both strands of DNA, which can cause ...

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, revolutionizing the ability to edit genes ...

While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology's edits are still imperfect. Researchers have developed a new system to test and analyze ...

The microbes that make up an organism’s microbiome have a range of effects on its health. Scientists use CRISPR systems to genetically manipulate specific bacterial species, for instance those found ...