这篇综述系统阐述了整合CRISPR/Cas9基因编辑技术与纳米颗粒（NPs）的创新策略，用于对抗生物膜（biofilm）介导的抗生素耐药性 ...

本研究首次在欧洲文昌鱼(B. lanceolatum)中建立CRISPR/Cas9基因编辑体系，通过靶向敲除bHLH转录因子Bl-Ascl1/2.1基因，证实其对表皮 ...

Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. The United Kingdom ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

Transthyretin amyloidosis with cardiomyopathy (ATTR-CM) is a progressive, often fatal disease. Nexiguran ziclumeran (nex-z) is an investigational therapy based on CRISPR-Cas9 (clustered regularly ...

Cas9 is directed to its target within the DNA sequence through the use of the guide RNA. A specific sequence of DNA that is between two and five nucleotides in length must align with the 3’ end of the ...

Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, ...

For the first time, U.S. regulators have cleared a treatment using CRISPR, the gene-editing technology, for patients. The product is Casgevy, a treatment for sickle cell disease and beta thalassemia, ...

Researchers have now used a gene-drive system to suppress an important agricultural pest. Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress ...

First-mover advantages are a big deal in the world of pharmaceuticals. CRISPR Therapeutics scored the first-ever regulatory approval for a CRISPR/Cas9 treatment this month. While logistical challenges ...