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Beginning with a brief historical overview of CRISPR, we will trace its evolution to the current state of gene engineering, highlighting its pivotal role in reshaping the landscape of molecular ...

本研究针对传统CRISPR-Cas系统挖掘方法的局限性，创新性地采用进化尺度语言模型（ESM）开发了AIL-Scan策略，成功鉴定了7种未记录的Cas12a亚型。通过整合机器学习与结构生物学技术，揭示了这些亚型独特的PAM识别特性和核酸酶活性，首次实现了无需传统PAM序列的 ...

Instead of pulling cells out of the body, editing them, and putting them back in, scientists have now found a way to send CRISPR tools directly to specific cells inside living animals. By wrapping ...

The accepted abstract titles are available online on the AHA website. The data in the abstracts and presentations are ...

When COVID first hit, waiting days for laboratory results from an ultrasensitive polymerase chain reaction (PCR) test was commonplace. Faster tests usable by anyone, anywhere, later became widely ...

本研究通过全基因组CRISPR/Cas9筛选发现组蛋白甲基转移酶SUV39H2是口腔鳞癌(OSCC)抵抗溶瘤病毒oHSV-1的关键因子。研究人员证实 ...

Vertex is severing one of its ties to CRISPR Therapeutics. The big biotech has chosen to opt out of the diabetes gene-edited stem cell therapy it gained through the acquisition of ViaCyte, leaving ...

CRISPR Therapeutics AG stock has surged nearly 90% since my Buy call in early May, reaching its highest value since February 2024. The rally builds on the historic approval of Casgevy, a gene editing ...