No. 13 Ole Miss will host the Tulane Green Wave in Week 4 with the Rebels set to square off against a non-conference foe at Vaught Hemingway Stadium. Lane Kiffi

Ole Miss vs Tulane preview, prediction, and betting lines. The Green Wave have the talent to trip up a Rebel team that might be looking toward next week.

The Tulane Green Wave and the No. 11 Ole Miss Rebels meet Saturday at Vaught-Hemingway Stadium in Oxford, Mississippi.

No. 13 Ole Miss will return to action on Saturday afternoon for a non-conference showdown against the Tulane Green Wave in Week 4. Lane Kiffin and Co. are riding a three-game winning streak to open the season with the program erupting on offense across the first three weeks.

The Tulane football team may be catching Ole Miss at the perfect time in between SEC home games with Arkansas and LSU, but the Green Wave already has expended plenty of energy itself in a 3-0 start with zero cupcakes.

Preview the Sept. 20 matchup between the Ole Miss Rebels and Tulane Green Wave with predictions, odds, over/under, spread, betting lines and more.

Find single game tickets to the Ole Miss Rebels vs. Tulane Green Wave college football Week 4 matchup on Saturday, September 20, 2025.

Tulane is relatively healthy entering Saturday's big road test at Ole Miss, but one running back and one defensive linemen have questionable availability according to coach Jon Sumrall.

No. 13 Ole Miss will return to action on Saturday night at Vaught Hemingway Stadium with the program preparing for a non-conference matchup against the Tulane G

Ole Miss football coach Lane Kiffin's team will play Tulane in Week 4. Here's how the Rebels shape up against the Green Wave.